Horizon Europe | Osiris

Science in houten letters gevormd

Reproducibility is crucial to progress and impact of Research and Innovation as it confirms or corrects the outcomes of single studies, resulting in higher quality research, more reliable and implementable outcomes, and reduction of research costs. Embedding reproducibility in the strategy and design of research should thus be regarded as a key precondition to research quality. Unfortunately, only a fraction of published studies can be reproduced due to e.g, science’s need to be continuously innovative, pressure to publish, a lack of transparent reporting, and career assessments based on quantity rather than quality. Currently, the burden of improving reproducibility lies with the researchers, as there are limited to no incentives to encourage active engagement in reproducibility and ideas for improvement have never been tested in practice.

We need a paradigm and culture shift to reform the system both from the top down and the bottom up to regain overall trust in science. Open Science to Increase Reproducibility In Science (OSIRIS) aims to facilitate this shift by systematically gathering knowledge on the underlying drivers, testing effective evidence-based solutions, identifying incentives for reproducibility by stakeholders, and embedding reproducibility in research design. This will be realised by a unique team with hands-on expertise in Open Science, reproducibility, implementation, and data sharing, along with a range of committed stakeholders that are closely involved through our Advisory Board.


  • UMCU ( The Netherlands)


  • Amsterdam UMC (Nederland)
  • Katholieke Universiteit Leuven (België)
  • Mario Negri Institute for Pharmacological Research (Italië)
  • Hungarian University of Agriculture and Life Science (Hongarije)
  • Czech University of Life Sciences (Tsjechië)
  • Young professionals for agricultural development (Tsjechië)
  • National Institute of Health and Medical Research (Frankrijk)
  • University of Oxford (Verenigd Koninkrijk)
  • Sense about Science (Verenigd Koninkrijk)


Horizon Europe


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